Director, Rare Disease RWE Scientist
Company: Pfizer
Location: Jackson
Posted on: January 22, 2023
Job Description:
ROLE SUMMARYThe Real-World Evidence (RWE) Center of Excellence
(CoE) is a rapidly expanding group that provides integrated,
end-to-end RWE optimization, education, communication, and
maximization of data partnerships' value within therapeutic areas
(TAs) to meet both core and innovative Development, Regulatory and
Commercial needs to support breakthroughs to change patients'
lives.The Rare Disease TA is responsible for creating and
commercializing therapies for rare disorders. Cross-functional
pipeline and asset teams create and deliver biologic medicines,
small molecules and exploratory gene therapies.Within the Global
RWE CoE, a dedicated team of RWE experts will support the TA.
Reporting to the Rare Disease RWE Senior Director, the RWE
Scientist Director will deliver timely feasibility assessments,
real world insights (RWI) and easy-to-understand summary reports by
understanding pipeline / asset teams' objectives and timelines.
They will co-develop RWE protocols in collaboration with the
cross-functional asset teams and RWE Biostatistics. The RWE
Scientist Director will provide guidance on the most appropriate
types of data and datasets for a given problem, and coordinate RWE
project execution with appropriate internal and external partner
analytic resources and tools. He/She will ensure the development of
consistent business rules, versioning rules as care pathways
evolve, standards and procedures.The RWE Scientist Director will
work closely with the RWE Senior Director and cross-functional
teams on assets' RWE strategy development. They will direct the RWE
cross-functional teams' work with pipeline/asset teams to integrate
RWE into their strategic plans and will use these plans to identify
key RWE teams' external data partnership opportunities. They will
oversee data procurement activities (e.g., landscape assessments
and due diligence or supporting contract development for external
studies). They will act as a subject matter expert in RWE studies
and take on projects independently. They will also have opportunity
to mentor/advise other RWE Scientists, directing their work.ROLE
RESPONSIBILITIES
- Act as the RWE subject matter expert for rare disease
franchise.
- Communicate and advocate effectively throughout the
organization to support the appropriate use of RWE.
- Educate colleagues throughout the organization on RWE enabled
use cases and best practices.
- Work collaboratively to ensure high quality methods and designs
throughout the product lifecycle from early clinical development to
loss of exclusivity.
- Conduct feasibility assessments to determine appropriate
internal/external real-world data sources
- Create RWI informing go/no-go decisions, hypothesis generation,
and decision-making for executives, teams, and business
development
- Coordinates cross-functional teams to create high quality RWE
from rigorously designed protocols
- Create TA-specific RWE assessment plans and recommend emerging
RWE analytical approaches
- Proactively identify opportunities for automation and
collaboration.
- Drive landscape assessments and evaluations of new
data/tools.
- Track market trends and regulatory standards
- Document all requests and track progress toward project
completion, other metrics and business goalsBASIC
QUALIFICATIONSCandidate demonstrates a breadth of diverse
leadership experiences and capabilities including: the ability to
influence and collaborate with peers, develop and coach others,
oversee and guide the work of other colleagues to achieve
meaningful outcomes and create business impact.
- 7+ (with a master's degree) to 9+ (Bachelor's degree) years'
experience with a proven successful track record of scientific
analysis for Non-Interventional Studies, other research studies or
clinical quality improvement studies, with specific experience with
a range of real-world data such as EHR, medical or pharmacy claims,
patient registries, or other data sources
- Five or more years of experience working in real world data
analytics in healthcare, clinical or translational research,
pharmaceutical Research & Development, or similar.
- Ability to critically evaluate analytic results against the
literature, subject matter expert feedback or other reliable
sources to ensure end user credibility in alignment with
cross-functional team strategy / priorities
- Five of more years of experience in communicating in verbal and
written form with all levels of personnel with diverse
backgrounds
- Ability to work under pressure with a high level of autonomy
and motivation
- Experience in Rare Disease domains, or the interest and ability
to rapidly learn these domains to understand and proactively apply
the latest scientific findings for projects
- Experience with protocol development and execution for
non-interventional studies using a variety of analytical techniques
applied to various databases
- Mentorship and leadership skills, particularly in highly
matrixed organizations
- Five or more years of hands-on experience of query and analytic
languages and technology platforms (eg, SQL, R, SAS, IHD, Aetion)
and of relevant biological and medical data standards (eg, HGNC /
Entrez, ICD, CPT)PREFERRED QUALIFICATIONS
- The ideal candidate will have a Master's degree with 9+
years/PhD with 7+ years in RWE analytics Economics, Bioinformatics,
Epidemiology, Other Biological Science fields with a substantial
quantitative and computational component, other related fields or
commensurate professional experience
- Experience with Sickle Cell Disease, Hemophilia, Duchenne's
Muscular Dystrophy, rare cardiac conditions, or other Rare Disease
priority areas highly desired
- Five or more years of experience in four or more of the
following:
- Experience in clinical registry, patient generated health data,
unstructured clinical data and other health data sources
- Understanding global regulatory guidance for appropriate use
and submission of RWE
- Knowledge of global HTAs' / payers' RWE acceptance, and
experience in value-based agreements, value-based care and similar
constructs
- Knowledge of efficient programming practices and the software
development life cycle
- Experience engaging or partnering with external organizations
(e.g., IDN, ACOs, payers, academic institute, professional
organizations, etc.) for RWE activities is strongly
- Artificial Intelligence (AI) / Machine Learning (ML): ability
and experience in creating advanced models to generate real world
insights
- Data Visualization: passion for and experience in generating
easy-to-use, interactive data visualization capabilities (e.g.,
Tableau, Spotfire)
- Clinicogenomics: understand the clinical application of
genomic, transcriptomic and other biomarker tests and result
reports as they pertain to clinical care or research
- Experience integrating real world evidence in early and late
clinical development.NON-STANDARD WORK SCHEDULE, TRAVEL OR
ENVIRONMENT REQUIREMENTSStandard working hours expected but may be
required to intermittently work longer hours during periods of high
demand. Limited travel to attend key internal business meetings or
conferences required.Other Job Details:Last Date to Apply for Job:
January 20th, 2023Additional Location Information: US- Remote;
Europe, Latin AmericaEligible for Relocation Package: No#LI-PFEFor
roles based in New York City: The annual base salary for this
position ranges from $150,900.00 to $251,400.00. In addition, this
position offers an annual bonus with a target of 20.0% of the base
salary and eligibility to participate in our share based long term
incentive program. Benefits offered include a retirement savings
plan, paid vacation, holiday and personal days, paid
caregiver/parental and medical leave, and health benefits to
include medical, prescription drug, dental and vision coverage in
accordance with the terms and conditions of the applicable
plans.Relocation assistance may be available based on business
needs and/or eligibility.Pfizer requires all U.S. new hires to be
fully vaccinated for COVID-19 prior to the first date of
employment. As required by applicable law, Pfizer will consider
requests for Reasonable Accommodations.Sunshine ActPfizer reports
payments and other transfers of value to health care providers as
required by federal and state transparency laws and implementing
regulations. These laws and regulations require Pfizer to provide
government agencies with information such as a health care
provider's name, address and the type of payments or other value
received, generally for public disclosure. Subject to further legal
review and statutory or regulatory clarification, which Pfizer
intends to pursue, reimbursement of recruiting expenses for
licensed physicians may constitute a reportable transfer of value
under the federal transparency law commonly known as the Sunshine
Act. Therefore, if you are a licensed physician who incurs
recruiting expenses as a result of interviewing with Pfizer that we
pay or reimburse, your name, address and the amount of payments
made currently will be reported to the government. If you have
questions regarding this matter, please do not hesitate to contact
your Talent Acquisition representative.EEO & Employment
EligibilityPfizer is committed to equal opportunity in the terms
and conditions of employment for all employees and job applicants
without regard to race, color, religion, sex, sexual orientation,
age, gender identity or gender expression, national origin,
disability or veteran status. Pfizer also complies with all
applicable national, state and local laws governing
nondiscrimination in employment as well as work authorization and
employment eligibility verification requirements of the Immigration
and Nationality Act and IRCA. Pfizer is an E-Verify employer.Market
Access#LI-PFE
Keywords: Pfizer, Jackson , Director, Rare Disease RWE Scientist, Executive , Jackson, Mississippi
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